OUTPUTS
Papers in Scientific Journals
Nunes, B., Cagide, F., Borges, A., Borges, F., & Simões, M. (2025). Antibacterial Effects of Novel Quaternary Ammonium and Phosphonium Salts against Staphylococcus aureus. Journal of Applied Microbiology, lxaf122. Advance online publication.
Pérez-Lavalle, L., Borges, A., Gomes, I. B., Carrasco, E., Valero, A., Simões, M. (2025). The ability of Salmonella enterica subsp. enterica strains to form biofilms on abiotic surfaces and their susceptibility to selected essential oil components. Letters in Applied Microbiology, 78(3): ovaf032
A. S. Gonçalves, J. R. Fernandes, M. J. Saavedra, N. M. Guimarães, C. Pereira, M. Simões and A. Borges. New insights on antibacterial mode of action of blue-light photoactivated berberine and curcumin-antibiotic combinations against Staphylococcus aureus. Photodiagnosis and Photodynamic Therapy, 2025, 104514.
Leitão, M. M., Gonçalves, A. S. C., Moreira, J., Fernades, C., Borges, F., Simões, M., & Borges, A. (2025). Unravelling the potential of natural chelating agents in the control of Staphylococcus aureus and Pseudomonas aeruginosa biofilms. European Journal of Medicinal Chemistry, 283, 117163.
Leitão, M. M., Gonçalves, A. S. C., Sousa, S. F. , Borges, F., Simões, M., & Borges, A. (2025). Two cinnamic acid derivatives as inhibitors of Pseudomonas aeruginosa las and pqs quorum-sensing systems: Impact on biofilm formation and virulence factors. Biomedicine & Pharmacotherapy, 187, 118090. DOI: 10.1016/j.biopha.2025.118090
Leitão, M. M., Gonçalves, A. S. C., Borges, F., Simões, M., & Borges, A. (2025). Polypharmacological strategies for infectious bacteria. Pharmacological reviews, 77(2), 100038. DOI: 10.1016/j.pharmr.2025.100038
Nunes, B., Cagide, F., Borges, A., Borges, F., & Simões, M. (2025). Antibacterial Effects of Novel Quaternary Ammonium and Phosphonium Salts against Staphylococcus aureus. Journal of applied microbiology, lxaf122. Advance online publication. DOI: 10.1093/jambio/lxaf122
Sousa, M., Machado, I., Simões, L.C., Simões, M, (2025). Biocides as drivers of antibiotic resistance: A critical review of environmental implications and public health risks. Environmental Science and Ecotechnology, 25, 100557. DOI: 10.1016/j.ese.2025.100557
Gonçalves, A. S. C., Leitão, M. M., Fernandes, J. R., Saavedra, M. J., Pereira, C., Simões, M., Borges, A. (2024). Photodynamic activation of phytochemical-antibiotic combinations for combatting Staphylococcus aureus from acute wound infections. Journal of Photochemistry & Photobiology, B: Biology, 258:112978. DOI: 10.1016/j.jphotobiol.2024.112978.
Gonzalez-Prada, I., Borges, A., Santos-Torres, B., Magariños, B., Simões, M., Concheiro, A., Alvarez-Lorenzo, C. (2024). Antimicrobial cyclodextrin-assisted electrospun fibers loaded with carvacrol, citronellol and cinnamic acid for wound healing. International Journal of Biological Macromolecules, 277(Part 3): 134154. DOI: 10.1016/j.ijbiomac.2024.134154.
Leitão, M. M., Vieira, T. F., Sousa, S. F., Borges, F., Simões, M., Borges, A. (2024). Dual action of benzaldehydes: inhibiting quorum sensing and enhancing antibiotic efficacy for controlling Pseudomonas aeruginosa biofilms. Microbial Pathogenesis, 191:106663. DOI: 10.1016/j.micpath.2024.106663.
Teixeira, L. S., Sousa, M., Massano, F., Borges, A. (2024). Exploring grape pomace extracts for the formulation of new bioactive multifunctional chitosan/alginate-based hydrogels for wound healing applications. Food Bioscience, 62:105073. DOI: 10.1016/j.fbio.2024.105073.
Vieira, T. F., Leitão, M. M., Cerqueira, N. M. F. S. A., Sousa, S. F., Borges, A., Simões, M. (2024). Montelukast and cefoperazone act as anti-quorum sensing and anti-biofilm agents against Pseudomonas aeruginosa. Journal of Applied Microbiology, 135(5):lxae088. DOI: 10.1093/jambio/lxae088.
Oral/ Poster Communications
M. M. Leitão, N. R. Filipovi’c, M. Simões and A. Borges. (2025) Targeting the Pseudomonas aeruginosa las quorum-sensing system with a pyridine-based thiazolyl-hydrazone to prevent biofilm-associated infections. Arturo Falaschi Conference “Cell-cell communication in bacteria: new insights and future trends”. 28-30 October 2025, Italy. (Poster)
Gonçalves, A. S. C., Borges, A., Simões M. Boosting Antimicrobial Photodynamic Inactivation of Pseudomonas aeruginosa Biofilms in Chronic Wounds with a Colistin-Berberine-Gentamicin Combination. The FEMS MICRO Milan 2025. 14 -17 July, 2025, Milan, Italy (Oral Presentation).
L. S. Teixeira, S. Fraga, M. Simões, A. Borges. Harmine-Antiseptic Dual Combination Photodynamic Therapy for Targeting Methicillin-Resistant Staphylococcus aureus. DCE25 – 6th Doctoral Congress in Engineering. 30 June – 1 July, 2025, Porto, Portugal (Poster Presentation).
Massano, F., Sousa, M., Borges, A., Simões, M. (2025). Selected monoterpenes as potential biofilm control agents and antibiotic resistance modifiers. DCE25 – 6th Doctoral Congress in Engineering. 30 June – 1 July, 2025, Porto, Portugal (Poster Presentation).
Silva, C., Teixeira, L. S., Simões, M., Borges, A. (2025). Synergistic approach to wound healing: combining natural photosensitizers and antiseptics (22975). In: IJUP 2025 – 18th Meeting of Young Researchers
L. S. Teixeira, S. Fraga, M. Simões, A. Borges. Combinations of Riboflavin with Antiseptics for Tackling Staphylococcus aureus Methicillin Resistant Infections by Photodynamic Inactivation. 4th International Electronic Conference on Antibiotics Challenges and Strategies for the Antibiotic Resistance Crisis. 21-23 May 2025, Online (Poster Presentation).
Teixeira, L. S., Fraga, S., Simões, M., Borges, A. Photodynamic inactivation of methicillin-resistant Staphylococcus aureus using harmine-antiseptic combinations. IV 1H-TOXRUN INTERNATIONAL CONGRESS 2025 – No Boundaries for Toxicology: One Health, One Society, One Planet. 8-9th May 2025 – Porto (Poster Presentation).
Borges, A. (2025). Phytochemicals in Focus: Research Approaches to Controlling Microbial Communities. 2nd UPorto Research Summer School in Microbial Communities: Taste of PhD Experience – Porto (Oral Presentation)
Gonçalves, A. S. C., Leitão, M. M., Simões, M., Borges, A. (2025) Antimicrobial Photodynamic Inactivation of Pseudomonas aeruginosa Biofilms: A Synergistic Approach with Berberine, Gentamicin, and Colistin. IV 1H-TOXRUN INTERNATIONAL CONGRESS 2025 – No Boundaries for Toxicology: One Health, One Society, One Planet. 8-9th May 2025 – Porto (Poster Presentation)
M. M. Leitão, F. Borges, M. Simões and A. Borges. (2025) Targeting quorum sensing: Ferulic and sinapic acids compromise Pseudomonas aeruginosa biofilm architecture and virulence. IV 1H-TOXRUN INTERNATIONAL CONGRESS 2025 – No Boundaries for Toxicology: One Health, One Society, One Planet. 8-9th May 2025 – Porto (Poster Presentation)
M. M. Leitão, M. Simões and A. Borges. (2025) Ferulic acid and sinapic acid attenuate Pseudomonas aeruginosa biofilm formation and virulence by targeting the pqs quorum sensing system. Biofilms 11 – Interdisciplinary Momentum: Accelerating Biofilm Research and Innovation Across Boundaries – Waler, UK (Poster Presentation)
M. Sousa, A. Borges, M. Simões. Development of new phytochemical-based disinfectant formulations for the control of healthcare-associated bacterial infections. IV 1H-TOXRUN INTERNATIONAL CONGRESS 2025 – No Boundaries for Toxicology: One Health, One Society, One Planet. 8-9th May 2025 – Porto (Oral Presentation)
Book Chapters
Deliverables
Commissariat à l’Énergie Atomique et aux Énergies Alternatives. (2025). GUIDELINES FOR THE MENTORSHIP PROGRAMME. Zenodo. https://doi.org/10.5281/zenodo.17492541
Faculty of Engineering – University of Porto (FEUP). (2025). METHODS FOR SHIKIMIC ACID ISOLATION AND PURIFICATION. Zenodo. https://doi.org/10.5281/zenodo.17348500
KPMG (Portugal). (2025). CATALOGUE OF INDUSTRIAL STAKEHOLDERS. Zenodo. https://doi.org/10.5281/zenodo.17348458
Simões, M., Afonso, A. C., Gomes, I., & Borges, A. (2025). D1.3 DATA MANAGEMENT PLAN FOR THE INNOVANTIBIOFILM PROJECT. Zenodo. https://doi.org/10.5281/zenodo.15280817
Simões, M., Borges, A., & Gomes, I. (2024). D6.1 COMMUNICATION, DISSEMINATION AND EXPLOITATION PLAN FOR THE INNOVANTIBIOFILM PROJECT. Zenodo. https://doi.org/10.5281/zenodo.14753657
Patents
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